2010. Vol. 52, N 12, p. 990–996
EFFECT OF OXYTOCIN ON ACTIVATION OF SPONTANEOUS ELECTRICAL ACTIVITIES REGISTERED FROM UTERINE CORPUS AND UTERINE TUBES IN RATS

K. V. Kazaryan, N. G. Hunanyan, I. B. Meliksetyan, R. R. Hakobyan, A. A. Savayan

L. A. Orbeli Institute of Physiology, National Academy of Sciences of Republic of Armenia, Yerevan;
e-mail: lmanvel@neuroscience.am

The effects if different concentrations of oxytocin (10-2, 10-1, 1 and 10 μg/kg) on burst duration and spikes frequency of spontaneous electrical activity in various parts of uterine horns and uterine corpus in non-pregnant rats have been shown. The changes in given parameters for ovarian parts of horns had similar characters unlike cervical parts of horns and middle part of uterine corpus under these conditions, so the last mentioned areas could be grouped together by the reason of similar changes in their parameters. Oxytocin in a concentration of 10-1 μg/kg promoted the longest duration of spike electrical activity genesis in ovarian parts of horns. Morphological experiments showed that ovarian parts of horns had a great amount of atypical cells with strongly expressed functional activities.

Key words:  oxytocin, uterine, cervical parts, uterine horn, spontaneous electrical activity


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