AGGREGATION OF METABOLICALLY DEPLETED HUMAN ERYTHROCYTES
Yu.A. Sheremet'ev,1 A.N. Popovicheva, M.M. Rogozin, G.Ya. Levin
Privolzhsky Federal Research Medical Centre, Ministry of Health of Russia, Nizhniy Novgorod, 603155;
1 e-mail: ya.sher@rambler.ru
An aggregation of erythrocytes in autologous plasma after blood storage for 14 days at 4 °C was studied using photometry and light microscopy. The decrease of ATP content,
the formation of echinocytes and sphero-echinocytes, the decrease of rouleaux form of erythrocyte aggregation were observed during the storage. On the other hand the aggregates
of echinocytes were formed in the stored blood. The addition of plasma from the fresh blood didn't restore the normal discocytic shape and aggregation of erythrocytes in the stored
blood. The possible mechanisms of erythrocytes and echinocytes aggregation are discussed.
Key words:
erythrocytes, aggregation, aggregate morphology, autologous plasma, rouleaux, echinocytes, blood storage
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