ANALYSIS OF THE DINOFLAGELLATE PROROCENTRUM MINIMUM TRANSCRIPTOME:
IDENTIFYING THE MEMBERS OF THE VOLTAGE-GATED CATION CHANNELS SUPERFAMILY
I.A. Pozdnyakov,1 S.O. Skarlato
Institute of Cytology RAS, St. Petersburg, 194064;
1 e-mail: pozdnyakov@cytspb.rssi.ru
Dinoflagellates are an ecologically important group of aquatic single-cell eukaryotes. At the present time
relatively little is known about physiological features that determine the role of these protists in natural ecosystems.
Lack of knowledge on the diversity, structure, and functioning of dinoflagellate ion channels significantly
hampers the interpretation of physiological reactions and adaptations in these microorganisms. We performed
the analysis of the translated transcriptome databases that belong to two strains of the dinoflagellate Prorocentrum
minimum in order to identify the members of the voltage-gated cation channels superfamily. We found out
that transcriptomes of these potentially toxic microorganisms contained the homologues of: 1) inwardly rectifying
potassium channels (Kir), 2) voltage-gated potassium channels (Kv), 3) calcium-activated potassium channels
(KCa), 4) cyclic nucleotide-gated channels (EAG and HCN/CNG), 5) TRPV and TRPP channels,
6) two-pore calcium channels TPC, 7) voltage-gated sodium (Nav) and calcium (Cav) channels, 8) voltage-gated
proton channels (Hv).
Key words:
unicellular eukaryotes, protists, dinoflagellates, ion channels, transcriptome
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