Tsitologiya  2014  56 (6) : 434–436
ANTIBODIES TO DNA STIMULATES DEATH OF MONONUCLEAR CELLS OF HEALTHY PERSONS IN VITRO

A.Z. Gavrilova, T. A. Nevzorova 1

Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University;
1 e-mail: TNevzorova@mail.ru

We have shown that polyclonal antibody IgG to native DNA leads to increased levels of apoptosis of mo-nonuclear cells of healthy persons in vitro. Possible biological role of antibodies to DNA is discussed.

Key words:  antibodies to DNA, systemic lupus erythematosus, apoptosis


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