Tsitologiya  2014  56 (6) : 399–409
THE PERICHROMATIN COMPARTMENT OF THE CELL NUCLEUS

D.S. Bogolyubov

Institute of Cytology RAS, St. Petersburg;
e-mail: dmitr@mail.cytspb.rssi.ru

In this review, the data on the structure and composition of the perichromatin compartment, a special border area between the condensed chromatin and the interchromatin space of the cell nucleus, are discussed in the light of the concept of nuclear functions in complex nuclear architectonics. Morphological features, molecular composition and functions of main extrachromosomal structures of the perichromatin compartment, perichro-matin fibrils (PFs) and perichromatin granules (PGs) including nuclear stress-bodies (nSBs) that are derivates of the PGs under heat shock, are presented. A special attention was paid to the features of the molecular compositions of PFs and PGs in different cell types and at different physiological conditions.

Key words:  cell nucleus, perichromatin compartment, perichromatin fibrils, perichromatin granules, nuclear stress-bodies


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