DEPENDENCE OF EFFICACY OF CELL GROWTH ON BIOSYNTHETIC MEDICINAL MATERIALS ON THE MICROSTRUCTURE OF THEIR SURFACE
V. Gavrilyuk,1 V.K. Ivanov,2 A.V. Kulikov,1 B.K. Gavrilyuk 1
1 Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow region,
2 Kurnakov Institute of General and Inorganic Chemistry, RAS,Moscow;
e-mail: gavrilyuk@mail.ru
The efficacy of the novel class was studied in which natural and synthetic polymeric components are arranged not in layers but in a unified structure, i. e., form a new
composite material. In particular, it was determined whether the interaction of dressing surface with cells of the injured tissue and/or culture grown in vitro depends on the
microstructure of the surface. The efficiency of cell growth has been considered from the viewpoint of the stimulation of cell growth. The microstructure of the surface was
studied by the method of high-resolution electron microscopy. The results of the study showed that the structure of biosynthetic dressings depends on the variations of the
composition and the ratio of components. The role of the microstructure of the dressing in the efficacy of its function was demonstrated. Factors producing the most significant
effect on the regenerating properties of wound dressings were revealed.
Key words: cell cultivating, wound dressings, microstructure of the dressing, regeneration
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