Tsitologiya  2013  55 (3) : 148–152

CONTEMPORARY APPROACHES TO B CHROMOSOME ANALYSIS A.I. Makunin,1,2,* V.A. Trifonov 1,3 1 Institute of Molecular and Cellular Biology SB RAS, Novosibirsk, 2 Theodosius Dobzhansky Center for Genome Bioinformatics of the Saint-Petersburg State University and 3 Novosibirsk State University; * e-mail: alex.makunin@gmail.com The most recent data on sequencing and analysis of non-coding genome parts revealed surprising biological functions of sequences, which were previously thought to be junk. Here we review the progress of techniques for B chromosome analysis – from methods of classical cytogenetics to contemporary technologies of high throughout genome sequencing, – and discuss the perspectives of involving new species with additional chromosome to ongoing genomic projects. Key words:  B chromosomes, whole-genome sequencing, genome analysis |  Back   |  Contents   |  Main  |