P ELEMENTS COMPRISING MINI-WHITE MARKER GENE SUPPRESSION FEATURES IN INTERGENIC REGIONS OF D. MELANOGASTER GENOME
V.N. Babenko, V. F. Matvienko
Insitute of Cytology and Genetics SB RAS, Novosibirsk;
e-mail: bob@bionet.nsc.ru
12492 intergenic regions were stratified into four classes according to protein coding genes mutual orientation flanking an intergenic region. It was revealed that transposon
insertion sites number linearly correlates with number of promoters (none, one, or two) in an intergenic region. The vast majority of transposons reside in intergenic regions with
two promoters. Remarkably, the suppression manifestation, on the contrary, was most pronounced in "promoterless" intergenic regions. Discussion of the phenomenon is based
on the chromatin state analysis of various intergenic regions.
Key words: Drosophila melanogaster, mutual gene orientation, chromatin, replication timing
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