GABA AND GLYCINE - INTERACTION OF RESPONCES AND RECEPTOR CROSS TALK
Amakhin D.V.1, Veselkin N.P.1,2
1 Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, Saint-Petersburg, and
2 Saint-Petersburg State University, department of Medicine;
e-mail: Dmitry.Amakhin@gmail.com
Today it is well accepted that GABA can be co-localized and co-released with glycine in the same synapse. This article provides an overview of GABA and glycine co-localization
and the effects of simultaneous activation of GABAA and glycine receptors. The review deals with mechanisms of direct and indirect receptor interaction, as well as with the effect of
non-selective activation of glycine receptors by GABA.
Key words: GABA, glycine, GABAa-receptors, glycine receptors
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