Tsitologiya  2012  54 (5) : 439–445
TELOMERE LENGTH IN THE POPULATION OF LONG-LIVED PERSONS
OF NORTH-WEST REGION OF RUSSIA

T.Yu. Smirnova,1,* A.L. Runov,1 M.S. Vonsky,1 D.L.Spivak,2
A.G. Zakharchuk,3 V.M. Mikhelson,1 I.M. Spivak 1

1 Institute of Cytology, RAS, 2 N.P. Bekhtereva Institute of Human Brain, RAS, 3 Gerontological Medico-Social Center, St.Petersburg, Russia;
* e-mail: tatiana.smirnova@live.ru

Interdisciplinary study of telomere length, polymorphism of genes of renin-angiotensin (ACE) and serotonin (5HTR2A and 5HTTPR) systems in population of aged and old inhabitants of the North-West of Russia was conducted, in their relations to data from clinical and geriatric anamnesis, and psychological functioning. Regular link between telomere length and respondent's age was demonstrated in subgroups of old respondents and long-livers, by method of factor analysis.


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