COMPARATIVE MORPHOLOGY OF TISSUES WHEN USING POLYPROPYLENE
AND POLYTETRAFLUORETILEN PROSTHESES
S.V. Ivanov, I.S. Ivanov, G.N. Gorjainova, A.V. Tsukanov, T.P. Katunina
Kursk State Medical University, Kursk;
e-mail: ivanov.is@mail.ru
The synthetic mesh is widely used for treatment of hernias. We conducted a comparative study of the morphological
pattern of inflammation, the cellular composition of tissues and dynamics of scar formation in mice
when using implants «Esfil» and «Unifleks» under influence of single and double injection of cultured fibroblast
and without such injection to the region of stents location. A more pronounced inflammatory reaction during
the study period of investigation was observed in the case of «Esfil». In the late period of the study, a higher
percentage of fibroblasts was observed in the case of the prosthesis «Unifleks» compared to the prosthesis «Esfil
». Injection of cultured fibroblasts modifies the curve of the dynamics of the inflammatory process by making
it smoother in the case of both prostheses. So, more preferred is the use of prostheses «Unifleks».
Key words: postoperative hernia, biopolymers, morphology, mesh stents, fibroblast
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