STABILITY OF BONE MARROW STROMAL CELLS TO LOW TEMPERATURES ACCORDING TO THEIR DEGREE OF DIFFERENTIATION
M. Raydan,1 N. A. Shubin,1 N. S. Nikolayenko,1 M. I. Blinova,1 G. G. Prokhorov,2 G. P. Pinaev 1
1 Institute of Cytology RAS and 2 International Institute of Cryomedicine, St. Petersburg;
1 e-mail: raydanmazen@yahoo.com
On the bases of earlier conducted research about the stability of heterogeneous population of keratinocytes to low temperatures according to their stages of differentiation this experiment'
studies in vitro the stability to low temperatures of rat bone marrow stromal cells before and after their adipocyte and osteocyte differentiation. Results show that bone marrow stromal
cells after their differentiation into either adipocytes or octeocytes became least stable to low temperatures. Findings may serve as foundation for further studies that may explain the changes
of processes and mechanisms that play a major role in BMSC stability to low temperatures according to their stage of differentiation.
Key words: BMSC, adipocyte and osteocyte differentiation, low temperatures
