NEUROGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS: A TRANSGENIC APPROACH
A. V. Shakhbazau,1,* S. M. Kosmacheva,2 N. A. Kartel,1 M. P. Potapnev 2
1 Institute of Genetics and Cytology of Natl. Acad. Sci. of Belarus Minsk, Belarus, and
2 Republic Centre for Haematology and Transfusiology, Minsk, Belarus;
* e-mail: shakhbazau@gmail.com
Mesenchymal stem cells (MSC), alongside with "traditional" osteogenic, chondrogenic and adipogenic differentiation potentials, are considered by many researches
as capable of giving rise to neurogenic lineage as well. We overview transgenic approaches to the study of neurogenic differentiation of MSC, including expression of
neurotrophic factors, signalling molecules and other transgenes with neurogenic properties.
Key words: mesenchymal stem cells, neurogenic differentiation, transgene, transduction
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