2010. Vol. 52, N 4, p. 311-316
BENEFICIAL ACTION OF THE LIPOSOMAL FORM OF DIHYDROQUERCETIN ON THE PROCESS OF SKIN REGENERATION AFTER THERMAL BURN

A. A. Naumov,1 M. M. Potselueva 1,2,*

1 Pushchino State University and 2 Sector of Functional Biochemistry,
Institute of Theoretical and Experimental Biophysics RAS, Pushchino;
* e-mail: mpotselueva@rambler.ru

It was found that the flavonoid of plant origin, dihydroquercetin, being localized in lecitin nanoparticles in the presence of amino acid, reduced inflammatory reactions in the wound zone after thermal burn. Application of the liposomal complex on burn trauma stabilized the endogenous antioxidant system and minimized the area of the secondary necrosis in burn wound. Also, intensification of skin regeneration and repair of hair follicles and sebaceous glands were observed.

Key words:  antioxidants, oxidative stress, thermal burn, skin structure, regeneration


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