POSTTRANSLATION REGULATION OF PROGRAMMABLE CELL EVENTS IN UNICELLULAR EUKARYOTES
I. V. Shemarova
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, St. Petersburg;
e-mail: shem@iephb.ru
The review considers the up to date achievements about posttranslational regulation of programmable cell events: growth, development, and apoptosis in
unicellular eukaryotes mediated by histone modifications and DNA metylation. Special attention is given to the evolution aspects of the problem.
Key words: unicellular eukaryotes, DNA metylation, histone modifications, Sir2, cell stress
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