DYNAMICS OF THE ANNULATE LAMELLAE IN DROSOPHILA SYNCYTIAL EMBRYOS
N. V. Gubanova,1 E. V. Kiseleva 2
Institute of Cytology and Genetics, Siberian Branch of the RAS, Novosibirsk;
e-mail: 1 nat@bionet.nsc.ru;
2 elka@bionet.nsc.ru
In eukaryotic cells, mitotic events are controlled by evolutionarily conserved cyclin-dependent kinases (cdk): these kinases phosphorylate cell proteins, which
causes structural reorganization of the entire cell. Our recent studies of Drosophila syncytial embryos have demonstrated that cdk1 activity is a key factor
that controls nuclear pore complex assembly/disassembly and affects the structure of cytoplasmic pores in the annulate. In this paper, we report a comparative
analysis of these cytoplasmic organelles throughout the cell-cycle and throughout the development of Drosophila syncytial embryos. Based on the results
obtained, it was presupposed that distribution of annulate lamellae containing cytoplasmic pores could reflect the inactivation of the mitotic kinase cdk1 in
Drosophila syncytial embryos.
Key words: annulate lamellae, cell cycle, cyclin-dependent kinase, cdk, cytoplasmic pores, nuclear pores, mitosis, syncytial embryos,
Drosophila
Back
Contents
Main
