2008. Vol. 50, N 2. p. 91-112
THE CENTROSOME — A RIDDLE OF THE «CELL PROCESSOR»

R. E. Uzbekov, I. B. Alieva

Electron Microscopy Department, A. N. Belozersky Research Institute of Physico-Chemical Biology, Moscow State University;
e-mail: rustuzbekov@aol.com and irina_alieva@belozersky.msu.ru

In the present review the description of history of the centrosome investigation is given and the current state of knowledge of this cellular structure in morphological, biochemical, and functional aspects is presented. Besides of the classical functions of the centrosome as a MT nucleating, MT ancoriging, and MT organizing center, the idea about the centrosome as a cellular regulating center and as a structural part of the mechanism operating dynamic morphology of a cell is discussed.

Key words:  centrosome, centriole, basal body, primary cilia, microtubules


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