POLARIZATION AND ASYMMETRIC DIVISION OF STEM CELLS
V. V. Terskikh,1 A. V. Vasiliev, E. A. Vorotelyak
N. K. Koltzov Institute of Developmental Biology, Moscow;
1 e-mail: terskikh@bk.ru
Asymmetric cell division observed in many groups of organisms has similar mechanisms suggesting conservatism
of the process. Asymmetric division of stem cells that reside in their niches is aimed to regulation of
cell proliferation and genome stability maintenance. But stem cells may also divide symmetrically depending on
situation. Alteration of mechanisms of asymmetric division might be one of the factors of neoplasm growth.
Key words: asymmetric division, stem cells, niche
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