FORMATION OF SPHERICAL COLONIES AS A PROPERTY OF STEM CELLS
A. N. Sukach,1, 2 E. N. Ivanov 3
1 Scientific-Research Institute of Biology, V. N. Karazin Kharkov National University,
2 Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences
of Ukraine, Kharkov, and
3 Institute of Dermatology and Venereology of the Academy of Medical Sciences of Ukraine, Kharkov;
1 e-mail: an_sukach@yahoo.co.uk
The report deals with the ability of embryonic cells harvested from the nervous, hematopoietic and
epithelial-muscular human tissues to form spheres during in vitro culturing. Judging from their own data and those
reported elsewhere, the authors have hypothesized that formation of spherical colonies in vitro is a common
feature of stem cells of various origin and varying degree of maturation. Probably, the formation of spheres provides
for development of stem cells according to the locations and their inner temporal programs, which are specific
and particular for every type of cells.
Key words: embryo, stem cell, colony formation, sphere, nuerosphere, cell culture
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