A STUDY OF MAST CELL FUNCNTIONAL ACTIVITY AT IMMOBILIZATIVE STRESS
O. S. Artashyan,1 B. G. Yushkov, E. A. Mukhlynina
Institute of Immunology and Physiology the Ural Branch of RAS, Ekaterinburg;
1 e-mail: art@cynos.utnet.ru
Response of mast cells to stress has a systemic character, being observed in organs both determining development
of stress reaction (thymus, bone marrow, adrenals, stomach, duodenum) and not participating in this process (skin,
liver). The reaction of mastocytes is manifested as a total degranulation. Mast cell secretion is regulatory by its
nature, and biologically active compound are released directly on the target cells. Along with degranulation, which
is observed in organs participating in stress reaction formation, migration of mast cells takes place, resulting in
their redistribution.
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