NEUROGLIAFORM CELLS: NEUROCHEMISTRY, SPATIAL ARRANGEMENT, AND THEIR ROLE IN THE NEOCORTICAL INHIBITORY SYSTEM
S. G. Kalinichenko,1 Yu. V. Dudina, P. A. Motavkin
Department of Histology, Vladivostok State Medical University, and Institute of Marine Biology,
Far East Branch of RAS, Vladivostok;
1 e-mail: kalin@mail.primorye.ru
The neurogliaform cells (NGFC) localized in area 4 of the human motor cortex were found to express choline acetyl
transferase (ChAT), GABA, and calbindin. ChAT-positive neurons were located in cortical layer II. Their dendrites
lay in a close proximity to those of pyramid cells, neighbouring neurogliaform cells, and bodies and dendrites of
other cortical neurons. The NGFCs revealed by Golgi staining fell into two groups. Cells of the first group had
locally (within cortical layer II) spreading axons, while those of the second group had axons extending into the
adjacent layers. Neurochemical heterogeneity of NGFCs is discussed in the context of information processing in
cortical modules and interaction of excitatory and inhibitory interneurons.
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