STRUCTURAL ORGANIZATION, FUNCTIONS AND DYNAMICS OF NUCLEAR PORES
N. V. Gubanova,1 K. N. Morozova, E. V. Kiseleva 2
Institute of Cytology and Genetics, Siberian Branch of the RAS, Novosibirsk;
e-mail: 1 nat@bionet.nsc.ru,
2 elka@bionet.nsc.ru
This review summarized data on the morphological and biochemical analysis of nuclear pore complexes, which are
complex organelles providing the route of passive and active nuclear-cytoplasmic transport to different molecules in
the eukaryotic cell. The morphology and functional role of nuclear pores in higher and lower eukaryotes, and
molecular aspects of the import and export of molecules from the nucleus are described in addition to factors
involved in the regulation of these process. Special attention has been paid to sequential steps of the nuclear pore
assembly in vitro and in vivo.
Key words: nuclear pores, nuclear-cytoplasmic transport, nuclear pore dynamic, mitosis
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