Vol. 48 (2006), N 10, p. 862-866
THE INFLUENCE OF PARTIAL ANDROGEN DEFICIENCY OF AGING MEN (PADAM) ON THE IMPULSE REGIME OF INCRETION OF SEVERAL HORMONES AND MITOTIC ACTIVITY

A. V. Pechersky,1,* V. F. Semiglazov,2 O. B. Loran,3 A. I. Karpischenko,4 V. I. Pechersky,5 V. I. Mazurov 1

1 St. Petersburg Medical Academy of Post-Graduate Studies,
2 The N. N. Petrov Research Institute of Oncology, St. Petersburg,
3 Russian Medical Academy of Post-Graduate Studies, Moscow,
4 Russian Military Medical Academy, and
5 P. F. Lestgaft State Academy of Physical Education, St. Petersburg;
* e-mail: a_pechersky@msn.com

This research work is devoted to an important subject - study of the impulse regime of the incretion of a series of hormones among men with partial androgen deficience of aging men (PADAM). The results of this study suggest that PADAM leads to a breakdown of the impulse regime of incretion of a series of hormones, including luteinizing hormone (LH), follicle stimulating hormone (FSH), and somatotropic hormones (STH), as well as cortisol and insulin among men of older age groups. These changes accompany the development of metabolic syndrome (X-syndrome); their development can be inversed through androgen-replacement therapy.

Key words:  testosterone, PADAM, LH, FSH, STH, cortisol, insulin


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