STRUCTURAL AND FUNCTIONAL ORGANIZATION OF Na+ TRANSPORT IN EPITHELIAL SYSTEMS.
I. EPITHELIAL Na+ CHANNELS
A. V. Melnitskaya, Z. I. Krutetskaya, O. E. Lebedev
Chair of Biophysics, St. Petersburg State University;
e-mail: zoya@mail.bio.pu.ru
The review summarizes recent data on the structural and functional organization and regulation mechanisms of
Na+ transport in epithelial systems. The review is focused on the structure, function, regulation and
pathology of epithelial Na+ channels, which are critical for Na+ homeostasis maintenance and
blood pressure control.
Key words: Na+ transport, epithelial systems, amiloride-sensitive Na+ channels
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