CHARACTERISTICS OF HUMAN MESENCHYMAL STEM CELLS ISOLATED FROM BONE MARROW AND ADIPOSE
TISSUE
A. S. Teplyashin, S. V. Korzhikova, S. Z. Sharifullina, N. I. Tchupikova,
M. S. Rostovskaya, I. P. Savchenkova 1
Institute of Stem Cell, Ltd Co, Moscow, Russia;
1 e-mail: IrinaSavtchcnkova@rambler.ru
Populations of human mesenchymal stem cells were derived from bone marrow and adipose tissue. Here analysis of six
individuals is represented. Cells were isolated, expanded and evaluated by the expression of surface antigens using flow cytometry. These
cells displayed similar characteristics for many markers. Cells isolated from bone marrow and adipose tissue were found to be
homogeneously positive for CD 13, CD44, CD90, CD105, and negative for CD45, CD34, CD31 and CD117. Besides, differences in surface
antigene CD10 expression between narrow and adipose tissue-derived cells were detected. All these findings indicate that both bone marrow
and adipose tissue are important sources of mesenchymal stem cells, which could be used in cell therapy protocols.
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