TYPICAL CHANGES OF LYMPHOCYTE SURFACE ARCHITECTONICS IN CHRONIC VIRAL INFECTION
I. O. Naslednikova,1 N. V. Ryazantseva, V. V. Novitskiy, M. A. Antoshina
Siberian State Medical University, Public Health Department of the Russian Federation, Tomsk, Russia;
1 e-mail: ira_naslednikova@mail.ru
With the use of scanning electron microscopy, lymphocyte surface architectonics has been described in cases of chronic
viral persistence at tick-borne (vernal) encephalitis, hepatitis types A and B, and Herpes simplex. In lymphocytic population smooth and
plicate cells in addition to cells with vesicles and outgrowths on the surface prevailed. The appearance of lymphocytes with a combined
type of superficial microrelief was registered. It is supposed that despite the variety of types of lymphocyte surface architectonics and
possible causes promoting their polymorphism, changes in superficial ultrastructure of immunocompetent cells for chronic viral infection
have a nonspecific character.
Key words: scanning electron microscopy, lymphocyte, chronic viral infection
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