THE INFLUENCE OF ALPHA-TOCOPHEROL AND SYNTHETIC ANTIOXIDANTS
ON MORPHO-FUNCTIONAL STATUS OF GONADOTROPIC CELLS FROM WHITE RAT ADENOHYPOPHYSIS
M. V. Kozak, D. L. Teply
Faculty of Anatomy and Physiology of Man and Animals, Astrakhan' State Pedagogical University
Morphometric indices of gonadotropic cells obtained from adenohypophysis of white rats, both males and females,
were investigated after treatment with alpha-tocopherol and synthetic antioxidants. The former stimulated
the functional status of gonadotropic cells revealed in a proportional increase in both nuclear and cytoplasmic
volumes. After the treatment with a synthetic antioxidant dibunolum, the volume of the cytoplasm increased in
gonadolropic cells of rats of different sexes. After the treatment with a water-soluble antioxidant emoxipinum,
the volume of the cytoplasm in gonadotropic cells increased only in males. The outcomes allow to consider
alpha-tocopherol, in contrast to from synthetic antioxidants, as one of the modulators of the functional
state of gonadotropic cells obtained from adenohypophysis.
Key words: antioxodants, alpha-tocopherol, emoxipinum, dibunolum, gonadotrophic cells
obtained from adenohypophysis
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