Vol. 45 (2003), ¹ 5, p. 526-531
PANGENOM

V. V. Tetz

St. Petersburg State Medical University after I. P. Pavlov;
e-mail: victort@spmu.rssi.ru

A conception of general interaction between genetic information of different organisms is formulated. A new concept "Pangenom" is proposed for description of the total sum of genes of living organisms and viruses. Features of the Pangenom structure and processes controlling its saving and variability are discussed. It is demonstrated that this conception may be used in medicine for the aims of prognosis of epidemic situation, in particular, of newly spreading pathogen development of new methods of prophylaxis and diagnostics of oncological diseases, and also of the evaluation of possible consequences of molecular genetics and gene engineering interventions.

Key words:  genome, variability, evolution


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