Vol. 45 (2003), ¹ 3, p. 255-270
THE MAMMALIAN CENTROMERE ORGANIZATION

N. I. Enukashvily, I. S. Kuznetsova, O. I. Podgornaya

Institute of Cytology RAS, St. Petersburg;
e-mail: natella@mail.cytspb.rssi.ru

Routine and recently obtained data on the pattern and fuctions of the mammalian centromeres and kinetochores have been reviewed. Several problems of kinetochore formation (centromere recognition, anap-hase checkpoint) are specially discussed, in addition to the role played by centromere DNA in the interphase nucleus consideration.

Key words:  mammalian centromeres, kinetochores, centromere DNA


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