Vol. 45 (2003), ¹ 2, p. 196-215
THE ROLE OF TYROSINE PHOSPHORYLATION IN REGULATION OF CELL PROLIFERATION AND DIFFERENTIATION IN THE LOWER EUKARYOTES

I. V. Shemarova

The I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, St. Petersburg;
e-mail: irina@lis.mail.iephb.ru

The review summarizes current data on signaling transduction mechanisms in some unicellular eukaryotes, based on sequential translation of phosphotyrosine signals from the cell surface to the nucleus.

Key words:  unicellular eukaryotes, intracellular signaling, tyrosine phosphorylation, proliferation, growth factors, tyrosine kinase, ÌÀÐÊ, STAT


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